MED17 antibody

Catalog No. ABIN7116122

The Rabbit Polyclonal anti-MED17 antibody has been validated for WB and ELISA. It is suitable to detect MED17 in samples from Human, Mouse and Rat.

Quick Overview for MED17 antibody (ABIN7116122)

Target: MED17 (Mediator Complex Subunit 17 (MED17))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MED17 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MED17 Antibody

Purpose: MED17 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: mediator complex subunit 17

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for MED17

Target: MED17 (Mediator Complex Subunit 17 (MED17))

Alternative Name: MED17

Background:

Synonyms: Mediator of RNA polymerase II transcription subunit 17|Activator-recruited cofactor 77 kDa component (ARC77)|Cofactor required for Sp1 transcriptional activation subunit 6 (CRSP complex subunit 6)|Mediator complex subunit 17|Thyroid hormone receptor-associated protein complex 80 kDa component (Trap80)|Transcriptional coactivator CRSP77|Vitamin D3 receptor-interacting protein complex 80 kDa component (DRIP80)|MED17|ARC77|CRSP6|DRIP77|DRIP80|TRAP80

Background: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Molecular Weight: 80 kDa

Gene ID: 9440

UniProt: Q9NVC6

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha